When Andy, Maya and Dean respond to a call, they find an injured woman with amnesia; but soon into the treatment process, they realize there is much more to her story. Meanwhile, Captain Sullivan takes Ben and Jack on a house call that quickly becomes a close call for the patient they're treating, while Ryan may not have seen the last of his father, Greg.

At the Observatory, Mokrani and Catherine clash over the fate to be reserved for Micah, whom Catherine considers to be a major source of information. Micah reveals to Catherine that she has to find Bill Ward. The latter, for his part, tries to find out more about Emily, still assailed by visions of Adina, the leader of the aliens urging him to kill Bill.

Without telling Emily or her parents anything, Bill decides with Zoe to test on Emily the biological weapon he hopes to be able to use against the aliens. Catherine, for her part, has had difficulty managing her grief since Mokrani's death. She now has only one thing on her mind: to find out who Bill Ward is and find him. Sophia is ready to help him, but Nathan hesitates.

Lou, feeling like M.O.D.O.K. is stifling his individuality ahead of his bar mitzvah, jumps into M.O.D.O.K.’s portal to Asgard. There, Lou is taken by a tribe of goblins known as Kobolds, but wins them over with his magic tricks and becomes their leader. He refuses to go back home with his dad, so M.O.D.O.K. takes control of an army of Asgardian warriors and wages war against his son. Eventually, M.O.D.O.K. and Lou strike a deal and use Lou's magic tricks to pacify the Kobolds. Meanwhile, the Super Adaptoid agrees to help young M.O.D.O.K.

Without telling Emily or her parents anything, Bill decides with Zoe to test on Emily the biological weapon he hopes to be able to use against the aliens. Catherine, for her part, has had difficulty managing her grief since Mokrani's death. She now has only one thing on her mind: to find out who Bill Ward is and find him. Sophia is ready to help him, but Nathan hesitates.

After being terminated from Chastain, Conrad has difficulty figuring out his next step and distracts himself by accompanying a patient on a zero-gravity adventure. In his first move as the new Chief of Surgery, Cain puts the doctors on a commission-based pay system, which causes Devon’s new intern to agree to a procedure before weighing the risks. Meanwhile, Mina struggles with taking care of Adaku’s baby and Bell’s supplement company get its big break.

In the aftermath of the windstorm, Andy and Sullivan's fates remain unknown while trapped in the overturned aid car. Meanwhile, back at the station, the team confronts Jack about his well-being; and when it's safe enough to venture out, they search for their fellow firefighters in a race against time.

The night is full of surprises on "Desperate Housewives" as we learn what has transpired on Wisteria Lane in the past five years. Driven by a hidden agenda, Dave convinces Susan to throw Mrs. McCluskey a surprise party for her 70th birthday; Jackson wants to take his relationship with Susan to the next level; Gaby's concerned she might be pregnant; Tom tells Lynette he's sold the pizzeria; a startling reason for the bond between Bree and Katherine is revealed; and an outraged Mrs. McCluskey has the entire neighborhood questioning her sanity.

"Hell hath no fury like a woman scorned," on "Desperate Housewives." Gaby is over the moon when Carlos' client makes them an offer they can't refuse, but a startling discovery leaves her second guessing; Lynette grows suspicious that Tom is cheating on her; and after breaking up with Jackson, Susan tries to surprise him, only to find the surprise is on her. Meanwhile, the bond between Bree and Katherine grows, and Mrs. McCluskey enlists the help of her sister to dig up dirt on Dave.

After being terminated from Chastain, Conrad has difficulty figuring out his next step and distracts himself by accompanying a patient on a zero-gravity adventure. In his first move as the new Chief of Surgery, Cain puts the doctors on a commission-based pay system, which causes Devon’s new intern to agree to a procedure before weighing the risks. Meanwhile, Mina struggles with taking care of Adaku’s baby and Bell’s supplement company get its big break.

Dr. Hamilton takes his frustrations out on Meredith, so Nick gives her a chance to blow off steam by scrubbing in on a surgery. Back in Seattle, Link and Jo take their kids to a fairytale theater performance that goes wrong. Bailey and Dr. Lin attend a recruitment fair in hopes of attracting more doctors to Grey Sloan but find themselves ill-prepared.

The doctors celebrate the holidays. Hamilton and Meredith prepare for a milestone on their project, while Link wants to spend the holiday with Amelia and Scout as a family. Schmitt is faced with a difficult decision during surgery.

The night is full of surprises on "Desperate Housewives" as we learn what has transpired on Wisteria Lane in the past five years. Driven by a hidden agenda, Dave convinces Susan to throw Mrs. McCluskey a surprise party for her 70th birthday; Jackson wants to take his relationship with Susan to the next level; Gaby's concerned she might be pregnant; Tom tells Lynette he's sold the pizzeria; a startling reason for the bond between Bree and Katherine is revealed; and an outraged Mrs. McCluskey has the entire neighborhood questioning her sanity.

"Hell hath no fury like a woman scorned," on "Desperate Housewives." Gaby is over the moon when Carlos' client makes them an offer they can't refuse, but a startling discovery leaves her second guessing; Lynette grows suspicious that Tom is cheating on her; and after breaking up with Jackson, Susan tries to surprise him, only to find the surprise is on her. Meanwhile, the bond between Bree and Katherine grows, and Mrs. McCluskey enlists the help of her sister to dig up dirt on Dave.

With Chastain on the verge of shutting down due to the sale by Red Rock, Conrad tries a last-ditch effort to save the hospital and the doctors plan for their next career moves. Meanwhile, on their last day, the whole staff must work together to save Nic’s life after she is injured by a deranged patient.

While working at their non-profit clinic three hours outside of Atlanta, Nic and Mina treat a patient with a failing heart VAD, forcing them to find a new battery in time to save her life. Conrad gets a call from a previous patent in crisis after being sued by Red Rock for medical expenses he can't afford. Meanwhile, Devon's VIP patient, Nadine, returns to the ER and Cain tries to get close to Bell's business partner from the supplement company.

The Grey Sloan Memorial doctors grapple with the aftermath of the car crash that involved some of their own. Meredith works to save Dr. Hamilton's life; Levi is impacted from his latest loss.

Schmitt must face the Morbidity and Mortality Conference. Meredith convinces Nick to scrub in on a surgery in Seattle. Jo faces her feelings.

Desire proves to be a dangerous emotion on "Desperate Housewives." Lynette and Tom uncover the unsettling truth about son Porter; Gabrielle suspects Carlos' best client has ulterior motives; Bree's moment of weakness could bring her great embarrassment and shame; and Katherine's not so little secret is unveiled. Meanwhile, Susan learns of Jackson's true passion, and Mrs. McCluskey's sister unearths a disturbing fact about Dave.

It will be a night to remember. Susan's daughter comes to visit with her surprising new boyfriend; Gaby uncovers the unsettling truth about Mrs. Hildebrand's past; Katherine has a confession to make to Susan; a reporter looks to expose Bree's imperfections; and Lynette learns Porter and Anne Schilling plan to leave Fairview and disappear. Meanwhile, everyone has gathered at a club to see the guys play in the annual "Battle of the Bands" when a fire erupts, threatening the lives of those in attendance. Some will fall as a hero will rise.

When Andy, Maya and Dean respond to a call, they find an injured woman with amnesia; but soon into the treatment process, they realize there is much more to her story. Meanwhile, Captain Sullivan takes Ben and Jack on a house call that quickly becomes a close call for the patient they're treating, while Ryan may not have seen the last of his father, Greg.

A plane crashes in Philadelphia due to a gunman opening fire while aloft. The crash hits the city's main power grid, Megan must conduct autopsies on the victims during frequent blackouts, but then one of the bodies goes missing.

An inmate violently escapes from a prison transport van. Then a witness in the escaped prisoner's murder trial is found dead. The accused murderer shows up and pleads with Megan that he is innocent and being framed.

With Chastain on the verge of shutting down due to the sale by Red Rock, Conrad tries a last-ditch effort to save the hospital and the doctors plan for their next career moves. Meanwhile, on their last day, the whole staff must work together to save Nic’s life after she is injured by a deranged patient.

The pressure of the Kennedy name weighs on John. Carolyn impresses at Calvin Klein. An unlikely connection forms at a charity event.

An inmate violently escapes from a prison transport van. Then a witness in the escaped prisoner's murder trial is found dead. The accused murderer shows up and pleads with Megan that he is innocent and being framed.

With Chastain on the verge of shutting down due to the sale by Red Rock, Conrad tries a last-ditch effort to save the hospital and the doctors plan for their next career moves. Meanwhile, on their last day, the whole staff must work together to save Nic’s life after she is injured by a deranged patient.

When Andy, Maya and Dean respond to a call, they find an injured woman with amnesia; but soon into the treatment process, they realize there is much more to her story. Meanwhile, Captain Sullivan takes Ben and Jack on a house call that quickly becomes a close call for the patient they're treating, while Ryan may not have seen the last of his father, Greg.

Desire proves to be a dangerous emotion on "Desperate Housewives." Lynette and Tom uncover the unsettling truth about son Porter; Gabrielle suspects Carlos' best client has ulterior motives; Bree's moment of weakness could bring her great embarrassment and shame; and Katherine's not so little secret is unveiled. Meanwhile, Susan learns of Jackson's true passion, and Mrs. McCluskey's sister unearths a disturbing fact about Dave.

It will be a night to remember. Susan's daughter comes to visit with her surprising new boyfriend; Gaby uncovers the unsettling truth about Mrs. Hildebrand's past; Katherine has a confession to make to Susan; a reporter looks to expose Bree's imperfections; and Lynette learns Porter and Anne Schilling plan to leave Fairview and disappear. Meanwhile, everyone has gathered at a club to see the guys play in the annual "Battle of the Bands" when a fire erupts, threatening the lives of those in attendance. Some will fall as a hero will rise.

Meredith, Amelia and the team prepare for Dr. Hamilton's long-awaited groundbreaking surgery while Bailey receives an unexpected offer. Owen's impatience makes him a difficult physical therapy patient, forcing Link to intervene.

Nick whisks Meredith away to his Minnesota cabin for a romantic weekend, leaving Winston and Maggie to care for Meredith’s children. Meanwhile, Amelia and Kai grow closer.

Upon meeting with a high-profile soccer player suffering from mysterious symptoms, Conrad ends up back at Chastain and faces an angry Logan Kim. When Bell and the Raptor come up empty-handed in regard to a diagnosis, the doctors take note on how talented Conrad truly is. Nic springs into action when she notices Kyle falling into a deep depression and fears he could be suicidal. Meanwhile, Devon butts heads with Irving over patient space and Mina realizes she has become attached to baby Michelle.